Division of Hematology, Oncology and Transplantation

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  • Committed to providing the highest quality care based on cutting edge research to patients with cancer or non-malignant hematologic diseases such as sickle cell disease

  • Dedicated to advancing research on the biological underpinnings of cancer, stem cell biology, sickle cell anemia, endothelial cell biology, and tumor immunology

  • Over 50 full-time academic investigators involved in interdisciplinary research and patient care are devoted to training the next generation of academic leaders

Division Chief

Dr. Weisdorf, Division Director for HOT

Daniel Weisdorf, MD

Announcements

Six faculty members in the Division of Hematology, Oncology, and Transplantation (HOT) were awarded grants from the Randy Shaver Cancer Research & Community Fund. With the support of these grants, Drs. Veronika Bachanova, Emil Lou, Manish Patel, David Potter, Deepali Sachdev, and Zohar Sachs will conduct innovative cancer research at the University of Minnesota. February 2017

Gregory Vercellotti, MD, FACP, received a $2 million R01 grant from the National Heart, Lung, and Blood Institute. With the support of this renewed grant, Dr. Vercellotti, Dr. John Belcher, and their research team will investigate the role of the innate immune system in sickle cell disease. These studies may lead to identification of new therapeutic targets for treating the devastating clinical symptoms of sickle cell disease. Please join us in congratulating Dr. Vercellotti,dr Belcher and their research team on their receipt of this prestigious, highly competitive award. January 2017

Shernan Holtan, MD received a 2017 Research Award for a clinical trial grant from Regenerative Medicine Minnesota, a state-wide initiative to improve the health of Minnesotans by advancing regenerative medicine therapies. With the support of this grant, Dr. Holtan will conduct a phase I/II clinical trial of a new regenerative therapy for patients with high-risk or steroid refractory acute graft-versus-host disease (GVHD). Acute GVHD is a frequent complication of allogeneic hematopoietic cell transplantation in which donor T cells attack the host's tissues, especially skin, intestine, and liver. Immunosuppressive therapy is the standard treatment for acute GVHD; however, it is ineffective in many patients. Dr. Hotlan will lead a clinical trial to determine whether growth factor supplementation in patients receiving standard immunosuppressive therapy is safe and more effective than immunosuppressive therapy alone. Please join us in congratulating Dr. Holtan on this important award. January 2017

Armin Rashidi, MD, PhD received a grant from the University of Minnesota Foundation to investigate the role of the gut microbiome in graft-versus-host disease (GVHD). GVHD is a frequent complication of allogeneic stem cell transplantation, a treatment given to patients with life-threatening blood diseases, such as leukemia, lymphoma, myeloma, and aplastic anemia. In allogeneic transplantation, stem cells are collected from a donor and transplanted into a patient to restore the patient's blood and immune system. In patients who develop GVHD, the donor's immune cells attack the patient's organs and tissues, impairing their ability to function. Dr. Rashidi and an interdisciplinary team of colleagues at the University of Minnesota will investigate whether a patient's gut bacteria protect them from developing GVHD. Please join us in congratulating Dr. Rashidi on receiving this award. January 2017