Newsletter continued . . .

DOM E-Newsletter - Summer 2019

CTSI Advances Support for Clinical Research

CTSI Advances Support for Clinical Research

CTSI Advances Support for Clinical Research

CTSI Advances Support for Clinical Research continued . . .

Investigators and research staff can walk-in, email, call or schedule appointments to get any and all of the assistance listed above. CRSC Research Navigators will assess investigator needs and connect them with the components of the CRSC to help in the development, deployment and initiation of a high-quality research protocol.

CRSC support is available to both new and seasoned investigators since the complexities of modern research protocols and assistance in shortening the time to open a trial can help everyone.

Feasibility Assessments. For the development of a new protocol, a formal feasibility review (at no charge) is also available. Available CRSC components including biostatistics, recruitment, contracting, regulatory, and other needs are reviewed in detail. Within one week, a formal meeting with the PI and staff plus a written report provides guidance and advice to improve a protocol and increase its likelihood of rapid regulatory approval. These feasibility reviews have gotten rave reviews from participants and most revised protocols have been approved with no or minor IRB stipulations. Contact the CRSC for more information.

New CTSI Medical Advisors. Drs. Byron Vaughn (Medicine GI) and Melena Bellin (Pediatrics Endocrinology) have joined as CTSI faculty. As active researchers they’ll be advising on Research Prep for protocols; Regulatory issues and a new CTSI initiative on Recruitment.

Research training thru CTSI-Ed. Training opportunities for research staff and investigators at all stages of their career (students, early career faculty, K awards, K to R01) are all available to provide guidance, training and collaborative capabilities to help researcher career development.

Clinical Research Support Center
Phone: (612) 625-4000
Email: umncrsc@umn.edu
Website: crsc.umn.edu

Daniel Weisdorf, MD ∙ Professor of Medicine, Deputy Director, CTSI

New/Renewal Federal Grants

New/Renewal Federal Grants

New/Renewal Federal Grants

Research continued

New/Renewal Federal Grants 

  • Anne Bantle: NIH ∙ "A Weight Neutral, High Protein, Moderate Carbohydrate Diet for the Treatment of Type 2 Diabetes Mellitus"
  • David Boulware: NIH∙ "Improving Diagnostics and Neurocognitive outcomes in HIV/Aids-related Meningitis"
  • Samuel Dudley: NIH ∙ "Training Program in Cardiac Innovation"
  • Daniel Garry: NIH ∙ "Mechanisms that Govern and Promote Cardiovascular Regeneration"
  • Alon Herschhorn: NIH ∙ "Delineation & Vulnerabilities of HIV-1 Escape from Neutralizing Antibodies"
  • Sarah Lofgren: NIH ∙ "Neuroinflammation and Modulating Factors in Depression and HIV"
  • Andrew Olson: Gordon & Betty Moore Foundation ∙ "Feedback, Calibration, and Improvement Improving Diagnostic Performance Through Evidence-Based Strategies"

Peter Crawford, MD, PhD
Vice Chair for Research

Paul Drawz, MD
Associate Chair, Clinical Research

Hennepin Health Care Logo

Clinical

Clinical

Hennepin Healthcare Clinical continued . . .
 
The Congestive Heart Failure (CHF) team for Hennepin Healthcare received the American Heart Association/American Stroke Association’s highest achievement in heart failure recognition with Get With The Guidelines® Heart Failure Gold achievement.
 
Minnesota Monthly Magazine Top Doctors, October 2018 issue, 59 Department of Medicine physicians were recognized in 14 specialties of Internal Medicine.
 
Mpls St. Paul Magazine Rising Stars, May 2019 issue: (practicing 10 years or less) 27 Department of Medicine physicians were recognized in 11 specialties of Internal Medicine.
 
Mpls St. Paul Magazine Top Doctors, July 2019 issue, 19 Department of Medicine physicians were recognized in 10 specialties of Internal Medicine.

Research

Research

Hennepin Healthcare Research continued . . .

The Clinical Pharmacology Division won an FDA contract for $10 million over five years, to examine the neurobehavioral pharmacology of tobacco products and constituents. The project will include collaborators from University of Minnesota, University of California Irvine and Georgetown University. 

Ajay Israni, Nephrology Division 

  • Creating a Patient-Centered Report Card for Solid Organ Transplant Candidates, R01 HS 24527. Annual Renewal
  • Gut Microbiota and Effect on Immune Suppressants in Transplantation. R01 DK118353. New 5-year grant, NIH 

Mark Linzer, General Internal Medicine Division 

  • Minnesota Learning Health System Mentored Career Development Program.  Five-year award from the Agency for Healthcare Research and Quality (AHRQ) and PCORI with the University of Minnesota and Mayo Clinic 
  • Impact of interventions on physician work conditions and patient trust. One-year grant award from the American Board of Internal Medicine Foundation  

Anne Murray, Geriatric Medicine Division 

  • Continuation of the BRain IN Kidney disease study (BRINK), $3.1 million, five-year RO1 NIH award  
  • Continuation of ASPREE – ASPirin in Reducing Events in the Elderly-as observational follow-on study, $6.2 million, NIH award  
  • As CTSI member, University of Minnesota CTSI for support for EPIC Data Warehouse Development, $780K, five-year award  

Martin Stillman, General Internal Medicine Division 

  • PI, Measuring and intervening burnout at a state level in three pre-selected states across the country with the American Medical Association (AMA) and Physicians Foundation. Extension of current grant with the AMA

Katherine Vickery, General Internal Medicine Division 

  • Stories for Change: Digital storytelling for Diabetes Self-Management among Hispanic Immigrants, Mayo Clinic, NIH R01. Site PI with co-investigator Rachel Silva, General Internal Medicine Division
  • Cross-sector data analysis to understand the role of Medicaid in out of home, Hennepin County
  • Improving medication adherence among people with diabetes who are homeless, NIH/NIDDK
  • Hotspotting cardiometabolic disparities for simulated advances in population health, NIH/NIA
  • Medication support for people with diabetes experiencing homelessness, NIH/NCATS
  • Selected as a Fall 2018 University of Minnesota CTSI KL2 Scholar in September 2018 

James B. Wetmore, Nephrology Division 

  • Burden of Illness, Clinical and Economic Characteristics of Dementia-Related Psychosis (DRP) Patients: A Longitudinal Analysis of Medicare Beneficiaries, $640,000 awarded from Acadia Pharmaceuticals for a one-year

Awards & Recognition

Awards & Recognition

Hennepin Healthcare Awards & Recognition continued . . .

Allyson Hart, Nephrology Division, Outstanding research poster presentation award at the annual University of Minnesota Clinical and Translational Science Institute (CTSI) poster session on September 12, 2018 titled: A shared decision-making tool for kidney transplant candidates. This was the third year in a row that she was the recipient among the KL2 scholars. Dr. Hart also was the winner of a $1,500 Travel Award for this poster.

David Hilden, Hospital Medicine Division
He began his term as Governor of the Minnesota Chapter of the American College of Physicians (ACP) following the Spring 2019 National Meeting.

Mark Linzer, General Internal Medicine Division

  • Top prize for a poster he was an author on: "Associations between treatment burden, medication adherence, and social vulnerability measures among patients with hypertension" in the summer Pathways to Research Program at the Annual University of Minnesota CTSI poster session, September 2018.
  • Received the 2018 University of Minnesota School of Public Health Community Partner STAR award, October 2018.
  • Nominated for the AMA Inspiration Award. This award recognizes physicians who have contributed to the achievements of women in the medical profession.

Arti Prasad, Department of Medicine Chief
Nominated to join the National Advisory Committee of the initiative FORESIGHT. She is the only physician from Minnesota who has received this honor.

Megan Shaughnessy, Infectious Diseases Division
Megan was one of two candidates selected for the University of Minnesota Medical School’s Office of Faculty Affairs’ sponsorship for the AAMC Early Career Women Faculty Leadership Development Seminar, February 2019, San Diego, California.

Haylee Veazey, General Internal Medicine Division
Received a Business Pride Award from the Minneapolis/St. Paul Business Journal in June 2019.

Education

Education

Hennepin Healthcare Education continued . . .

  • Rheumatologist, Dr. Rawad Nasr, joined the Medicine Education Program as an Associate Program Director in January of 2019, and has had a broad, positive impact on the residency. Dr. Nasr is mentoring resident scholarly activities and publications, helped with facilitatating continuity clinic changes to achieve Medicine Clinic level-loading, organizes resident presentations of challenging rheumatology cases at Morning Report, added core rheumatology content to clinic immersion blocks, and brings great perspective, clinical and educational wisdom to Program Evaluation and Clinical Competency Committee meetings.

  • Banner year for local and international global health activities.  Dr. Megan Shaughnessy, Infectious Diseases Division, is our new site director for the Global Health Program. Resources in the Global Health Pathway continue to be accessed by many residents, which include: 5 who completed the University of Minnesota’s Global Health Course in May; 6 that traveled to countries all over the world, including Laos, Thailand, Tanzania, Cameroon and Columbia; and 3 that enrolled in the Migrant Health summer elective to provide care to migrant workers through mobile clinics, get hands-on exposure to conditions in fields and factories where migrants work, and learn from immigration lawyers, community members and faculty at Hennepin and the University of Minnesota. The residency also helped a senior resident attend a compassion retreat with the Dalai Lama in preparation for entering the National Health Services Corps after graduation and joining a rural Federally Qualified Health Center in Washington State.

  • Very successful 2018-19 recruitment. We matched a talented and diverse intern class with 58% women, 42% physicians of color and 21% from underrepresented minorities. Our fellowship match was equally successful, with graduates matching in Pulmonary-Critical Care at Indiana University and Maine Medical Center; GI at Cedars Sinai in Los Angeles; ID at OHSU; Nephrology at VCU; Critical Care at Brown; Sleep Medicine at the University of Missouri-Kansas City; Addiction Medicine at Mount Sinai in New York; and Toxicology and Endocrinology at the University of Minnesota. Our Cardiology, Critical Care, Sleep, Geriatrics and Nephrology fellowships recruit well and match excellent fellows and our brand new Informatics fellowship.

  • As Hennepin Healthcare diversifies its faculty, services and partnerships and finds new and innovative ways to effectively care for the most vulnerable people in our community, the core internal medicine residency and fellowships will continue to attract and train exceptional physicians that are passionate about supporting our mission.

Noteworthy Journal Publications

Noteworthy Journal Publications

Hennepin Healthcare Noteworthy Journal Publications continued . . .

Hart A, Gustafson SK, Wey A, Salkowski N, Snyder JJ, Kasiske BL, Israni AK. The association between loss of Medicare, immunosuppressive medication use, and kidney transplant outcomes. Am J Transplant. 2019;19(7):1964-1971.

Linzer M, Poplau S, Prasad K, Khullar D, Brown R, Varkey A, Yale S, Grossman E, Williams E, Sinsky C. Clinician trust in healthcare organizations. JAMA Netw Open. 2019(6)2:2019e196201.

Morrison VA, Shou Y, Bell JA, Hamilton L, Ogbonnaya A, Raju A, Hennenfent K, Eaddy M, Galaznik A. Treatment patterns and survival outcomes in patients with follicular lymphoma: A 2007 to 2015 Humedica database study. Clin Lymphoma Myeloma Leuk. 2019;19(4):e172-e183.

Shaughnessy MK, Snider T, Sepulveda R, Boxrud D, et al. Prevalence and Molecular Characteristics of Clostridium difficile in Retail Meats, Food-producing and companion animals, and humans in Minnesota. J Food Prot. 2018;81(10):1635-1642.

Vickery KD, Bodurtha P, Winkelman TNA, Hougham C, Owen R, Legler MS, Erickson E, Davis MM. Cross-sector service use among high health care utilizers in Minnesota after Medicaid Expansion. Health Affairs. 2018;37(1).

Vickery KD, Shippee ND, Bodurtha P, Guzman-Corrales LM, Reamer E, Soderlund D, Abel S, Robertshaw D, Gelberg L. Identifying homeless medicaid enrollees using enrollment addresses. Health Services Research. 2018; 53(3).

Wetmore JB, Peng Y, Gilbertson DT, Liu J. Relation of race, apparent disability, and stroke risk with warfarin prescribing for atrial fibrillation in patients receiving maintenance hemodialysis. Am J Cardiol. 2019;123(4):598-604.

Winkelman TNA, Admon LK, Jennings L, Shippee ND, Richardson CR, Bart G. Evaluation of amphetamine-related hospitalizations and associated clinical outcomes and costs in the United States. JAMA Network Open. 2018;1(6).

Arti Prasad, MD, FACP
Scott F. Davies Endowed Chair
Chief, Department of Medicine
Hennepin Healthcare

2019 Faculty Promotions

Promoted to Associate Professor

Promoted to Associate Professor

Wayne Adkisson ∙ Cardio
Paul Drawz ∙ Renal
Briar Duffy ∙ GIM
Sophia Gladding ∙  GIM
Shernan Holtan ∙ HOT
Mark Klein ∙ HOT/VA
Benji Mathews ∙ Regions
Amir Moheet ∙ Endo
Andrew Olson ∙ GIM
Manish Patel ∙ HOT
Matthew Prekker ∙ PACCS/HCMC
Daniel Schnobrich ∙ GIM
Chetan Shenoy ∙ Cardio
Gyorgy Simon ∙ GIM/IHI Joint
Guisheng Song ∙ Gastro
Richard Spong ∙ Renal
Julie Thompson ∙ Gastro
Jop van Berlo ∙ Cardio

Promoted to Professor

Promoted to Professor

Selcuk Adabag ∙ Cardio/VA
Gavin Bart ∙ GIM/HCMC
David Boulware ∙ IDIM
Gary Bryant ∙ Rheum
Lynn Burmeister ∙ Endo
Jane Chen ∙ Cardio
Susan Everson-Rose ∙ GIM
Howard Fink ∙ GIM/VA
Mohamed Hassan ∙ Gastro
Susan Kline ∙ IDIM
Erin Krebs ∙ GIM/VA
Doug Mashek ∙ Endo/BMBB Joint
Ganesh Raveendran ∙ Cardio
Venkat Tholokanahali ∙ Cardio/VA