Basic Research

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Research in the Laboratory of Dr. Meri Firpo

The focus of the Firpo Lab is the regulation of stem cell growth, both from the perspective of the expansion of stem cells in the lab, and the regulated differentiation to functional tissues. The overall goal of our research is to understand the regulation of human development. The research can be divided into two main directions: the first involves improvements in the derivation and propagation of human embryonic stem cells (hESCs); the second is the development of stem cell-based therapies for diabetes.

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Research in the Laboratory of Dr. Doug Mashek

A primary focus of our laboratory is on lipid droplet biology. Specifically, we are interested in the role of lipid droplets in the context of non-alcoholic fatty liver disease, Type 2 Diabetes and aging. Our studies use a broad range of models and methodologies that ultimately link nutrition, biochemistry and physiology (i.e. metabolism) to disease etiology.

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