Susan Kline, MD, MPH

Associate Professor of Medicine, Division of Infectious Diseases and International Medicine

Susan Kline

Contact Info

Mailing Address:
Division of Infectious Disease and International Medicine
420 Delaware Street SE
MMC 250
Minneapolis, MN 55455

Administrative Assistant Name

Administrative Phone

Administrative Email

Associate Professor of Medicine, Division of Infectious Diseases and International Medicine

Infectious Disease Physician

Medical School, University of Minnesota, Minneapolis, MN

Residency, University of Minnesota, Minneapolis, MN

Fellowship, University of Minnesota, Minneapolis, MN

Bachelor's Degree, University of Colorado, Boulder, CO


After graduating from the University of Minnesota Medical School in 1988, Dr. Kline completed her Internal Medicine residency at the University of Minnesota Medical Center and its affiliated sites. Following completion of her residency she worked in General Internal Medicine and Emergency Medicine for one year at the University of Minnesota Medical Center. She then began her Infectious Disease Fellowship at the University of Minnesota Medical Center and affiliated sites. She also completed her Masters in Public Health during her ID fellowship with an emphasis in Infectious Disease Epidemiology. Dr. Kline then for joined the Internal Medicine faculty in 1994 and is currently an Associate Professor. In addition she has been the Medical Director for Infection Control at the University of Minnesota Medical Center since 1996. She helped establish the Antibiotic Management Team at the University of Minnesota Medical Center in 2007. She currently is the Co-Director of the General Infectious Disease service and the Physician Director of Antimicrobial Management for the ID Division. She also is Co-Director of the HIV Family Clinic in the Delaware Street Clinic. She is the Hospital Epidemiologists for the University of Minnesota Medical Center.

Awards & Recognition

  • Best Doctors in America® (2011-2012)
  • Recipient of Department of Medicine Clinical Excellence Award (September, 2009)
  • Alpha Omega Alpha Medical Society–University of Minnesota Medical School (1987)
  • Delta Omega Honorary Public Health Society 1995
  • Faculty Clinical Excellence Award, Department of Medicine, University of Minnesota (2004, 2009)

Professional Associations

  • Medical Director of Infection Control, University of Minnesota Health
  • Fellow, Society of Hospital Epidemiologists of America (2010)
  • Member, Infectious Disease Society of America (IDSA) (1994-present)


Research Summary/Interests

Her research interests include the epidemiology of healthcare associated infections and prevention of these infections. In addition to her work on Infection Control and Antibiotic Decision Support systems Susan Kline is currently conducting a randomized clinical trial, “Effectiveness of Screening and Decolonization of S. aureus in Surgery Outpatients”. She recently completed another RCT in 2013, “A Trial for the Safety and Effectiveness of a Novel Antimicrobial-Coated Foley Catheter for Reduction of CAUTI”.


  • Siedelmann L, Duval S, Kline, S. Risk factors for community and health facility acquired extended- spectrum beta-lactamase producing bacterial infections in patients at the University of Minnesota Medical Center, Fairview. Am J Infect Control 2012;40:849-853. PMID: 22325481
  • DeVries A, Harper J, Murray A, Lexau C, Bahta L, Christensen J, Cebelinski E, Fuller S, Kline S, Wallace G, Shaw J, Burns C, Lynfield R. Vaccine-derived poliomyelitis 12 Years after infection in Minnesota, 2008. N Engl J Med 2011;364:2316-2323. PMID: 21675890
  • Wudhikaran K, Perry E, Kemperman M, Kline S, Severe transfusion transmitted babesiosis in an immunocompromised patient: report of a case. Am J Med. 2011;124:800-805.PMID: 21683324
  • Boyle-Vavra S, Gourley BL, Ruf R, Balsam AR, Boulware DR, Kline S, Jones M, Peterson S, Holme M, Daum R, DeVries A. Comparative genome sequencing of an isogenic pair of clinical MRSA isolates obtained during and after daptomycin treatment failure. Antimicrob Agents Chemother 2011;55:2018–2025. PMID: 213434416
  • Jongwutiwes U, Yanagida T, Ito A, Kline S. Isolated intradural-extramedullary spinal cysticercosis: a case report. J Travel Med 2011;18:284-287. PMID: 21722242
  • Fulton D, Kline S. Tuberculosis at the University of Minnesota Medical Center 2000-2006: a brief report. Minn Med 2010;93(6):50-52. PMID: 20827957
  • Kline S, Cameron S, Streifel A, Yakrus M, Kairis F, Peacock K, Besser J, Cooksey R. An outbreak of bacteremias associated with Mycobacterium mucogenicum in a hospital water supply. Infect Control Hosp Epidemiol 2004;25(12):1042-1049. PMID:15636290
  • Kline S, Hedemark L, Davies S. Outbreak of tuberculosis among customers of a neighborhood bar. N Engl J Med 1995;333:222-227. PMID: 7791838


Academic Interests and Focus

Course Director HIV Clinic elective rotation for Internal Medicine residents; Bedside teaching of medical students, residents and fellows; Co-Director Emerging Infections CME course



  • Infectious Disease


Delaware Street Clinic (Infectious Disease/HIV Clinic)

Board Certifications

  • Infectious Diseases and Internal Medicine

Clinical Interests

Her clinical interests include general infectious diseases, TB, tropical infectious diseases and HIV/AIDs, including prevention of perinatal transmission of HIV. She sees patients in the Delaware Street Clinic and does ID consultations in the University of Minnesota Medical Center; Antibiotic Management Team