Joan Beckman, MD, PhD

Assistant Professor of Medicine, Division of Hematology, Oncology and Transplantation

Joan Beckman

Contact Info

Mailing Address:
420 Delaware Street SE
MMC 480
Minneapolis, MN 55455

Lab Address:
Beckman Laboratory
516 Delaware Street SE
PWB 14-155
Minneapolis, MN 55455

Administrative Assistant Name
Amy Eisenberg

Administrative Email
eisenbea@umn.edu

Assistant Professor of Medicine, Division of Hematology, Oncology and Transplantation


Hematologist


MD, University of Minnesota Medical School, Minneapolis, Minnesota

Internal Medicine Residency, University of North Carolina Hospitals, Chapel Hill, North Carolina

Hematology Fellowship, University of North Carolina Hospitals, Chapel Hill, North Carolina

PhD, Cancer Biology, University of Minnesota, Minneapolis, Minnesota

BS, North Dakota State University, Fargo, North Dakota

Summary

I am a dedicated physician-scientist who is passionate about caring for patients with benign hematologic conditions. I have a clinical interest in patients with acquired and congenital bleeding disorders as well as patients with anemia. I conduct translational research in the molecular and cellular mechanisms driving inflammation-induced pathology in endothelial cells and blood vessels My current research focuses on evaluating the contribution of red blood cell and endothelial cell interactions in JAK2 V617F and CALR+ myeloproliferative neoplasm patients. 

Expertise

  • Endothelial Biology
  • Hemophilia
  • Rare Coagulation Disorders
  • Venous Thrombosis
  • Iron Deficiency Anemia
  • Hemoglobinpathies
  • Hereditary Hemorrhagic Telangiectasia (HHT)

Awards & Recognition

  • American Society of Hematology Travel Award (2014, 2008)
  • P.E.O. Scholar Award (2011)
  • Schmit-Steer Award, Minnesota Medical Foundation, Minneapolis, MN (2010)
  • Midwestern Section American Federation for Medical Research Junior Scholar Award (2010, 2009, 2008)
  • Central Society for Clinical Research Trainee Travel Award (2010, 2009, 2008)
  • J. Thomas Livermore Memorial Award, Minnesota Medical Foundation, Minneapolis, MN (2009)
  • Travel Award, 6th International Congress on Heme Oxygenases, Miami Beach, FL (2008)
  • Best Poster Award American Physician Scientists Association (APSA)/American Society for Clinical Investigation/Association of American Physicians (ASCI/AAP) Meeting, Chicago, IL (2008)
  • Science Award, National Institutes of Health Workshop on Vasculopathy in Sickle Cell Disease, Natcher Conference Center, Bethesda, MD (2008)
  • Best Poster Award, Department of Medicine Robert P. Hebbel Research Day (2008)

Professional Associations

  • Hemostasis & Thrombosis Research Society
  • American College of Physicians
  • American Society of Hematology
  • International Society for Haemostasis and Thrombosis

Research

Research Summary/Interests

  • Role of endothelial biology in inflammation-mediated coagulation disorders
  • Mechanisms to treat and or prevent bleeding and thrombosis in patients with myeloproliferative disorders
  • Mechanisms to identify bleeding phenotype in patients with hemophilia
  • Role of endothelium in sickle cell pathogensis

Publications

  • Beckman, J.D., Rollins-Raval, M.A., Raval, J.S., Park, Y.A., Mazepa, M., Ma, A. 2017. Bortezomib for Refractory Immune-Mediated Thrombocytopenia Purpura (ITP). Am J Ther. 25(2):e270-e272. doi:10.1097/MJT.0000000000000517.
  • Beckman JD, Holle, LA, Wolberg AS. 2018. Factor XIII Co-Treatment with Hemostatic Agents in Hemophilia A Increases Fibrin ?-Chain Crosslinking.J Thromb Haemost. 16 (1); 131-141.
  • Walton BL, Lehmann M, Skorczewski T, Holle LA, Beckman JD, Cribb JA, Mooberry MJ, Wufsus AR, Cooley BC, Homeister JW, Pawlinski R, Falvo MR, Key NS, Fogelson AL, Neeves KB, Wolberg AS.2017. Elevated hematocrit enchances platelet accumulation following vascular injury. Blood. 129: 2537-46.
  • Beckman JD, Chen CS, Nguyen J, Thayanithy V, Subramanian S, Steer CJ, Vercellotti GM. 2011. Regulation of Heme Oxygenase-1 Protein Expression by miR-377 in Combination with miR-217. Journal of Biological Chemistry 286(5):3194-3202.
  • Belcher JD, Beckman JD, Balla G, Balla J, Vercellotti G. 2010. Heme Degradation and Vascular Injury. Antioxidants & Redox Signaling 12(2):233-248.
  • Belcher JD, Vineyard JV, Bruzzone CM, Chen CS, Beckman JD, Nguyen J, Steer CJ, Vercellotti GM. 2010. Heme oxygenase-1 gene delivery by Sleeping Beauty inhibits vascular stasis in a murine model of sickle cell disease. Journal of Molecular Medicine. 88(7):665-675.
  • Beckman JD, Belcher JD, Vineyard JV, Chen CS, Nguyen J, Nwaneri MO, O'Sullivan MG, Gulbahce E, Hebbel RP, Vercellotti GM. 2009. Inhaled carbon monoxide reduces leukocytosis in a murine model of sickle cell disease. American Journal of Physiology-Heart and Circulatory Physiology 297(4):H1243-H1253.
  • Bruzzone CM, Belcher JD, Schuld NJ, Newman KA, Vineyard J, Nguyen J, Chen C, Beckman JD, Steer CJ, Vercellotti GM. 2008. Quantitative real-time polymerase chain reaction (qRT-PCR) restriction fragment length polymorphism (RFLP) method for monitoring highly conserved transgene expression during gene therapy. Translational Research 152(6):290-297.
  • Beckman JD, Grazul-Bilska AT, Johnson ML, Reynolds LP, Redmer DA. 2006. Isolation and characterization of ovine luteal pericytes and effects of nitric oxide on pericyte expression of angiogenic factors. Endocrine 29(3):467-476.

Teaching

Academic Interests and Focus

My on campus teaching involves case based training and teaching in the clinic as well as within the Hematology/Oncology Fellowship Program.

Teaching Areas

    Clinical

    Clinics

    Center for Bleeding and Clotting Disorders;Masonic Cancer Center

    Board Certifications

    • Hematology

    Clinical Interests

    Hemophilia; Bleeding and Clotting Disorders; Iron Deficiency; Hemochromatosis; Heminglobinopathies, including Sickle Cell Disease; Myeloproliferative Neoplasms; Erythrocytosis; Thrombocytosis; Thrombocytopenia

    Hospital Privileges

    Fairview Northland Medical Center; Fairview Ridges Hospital; Fairview Southdale Hospital; University of Minnesota Medical Center; Fairview Lakes Medical Center