Smarika Sapkota, MBBS

Assistant Professor of Medicine, Division of General Internal Medicine

Smarika Sapkota

Contact Info

Office Phone 612-626-4603

Mailing Address:
420 Delaware Street SE
MMC 741
Minneapolis, MN 55455

Administrative Assistant Name
Madison Stangl

Administrative Phone

Administrative Email

Assistant Professor of Medicine, Division of General Internal Medicine

MD, Medical School, Kathmandu University School of Medical Sciences, Kavre, Nepal

Internal Medicine Residency, University of Minnesota, Minneapolis, Minnesota


I completed my residency from University of Minnesota. My research so far has been in diverse areas. I started out with research on pediatric nephrology; then enrolled in research in gastroenterology and hepatology during my internship. I am currently working on clinical research in Clostridium difficile in transplant population and treatment outcome for leukemia. My aim is to broaden clinical research experience in hematology and rheumatology. My teaching experience goes back to my home country Nepal where I have worked with medical students as a medical officer in emergency department. And I feel fortunate to continue that here in residency and now as a faculty. My clinical experience starts from my home country in Nepal. I worked there as a medical officer in emergency department in a Teaching Hospital and in internal medicine department in a Community Hospital for total 2 years before joining residency. I also worked as a research assistant in Long Island Jewish Hospital in New York before residency.


Research Summary/Interests

  • Clostridium difficile infection in solid organ and hematopoietic stem cell transplant
  • Axios stent in the treatment of pancreatico-biliary and gastrointestinal disorder
  • Discontinuation of inappropriate PPI use in Primary Care setting (QI)
  • Use of appropriate dose statin for secondary prevention in CVD in Primary care setting (QI)
  • Acute kidney injury (Published chapter in Rogers Pediatric critical care)
  • Clofarabine and cytarabine combination therapy for Acute Myeloid Leukemia in newly diagnosed and relapsed and refractory patients (ongoing)
  • Incidence of Hypertension in patients undergoing surgery (in Kathmandu, Nepal)
  • Incidence of Colorectal Cancer based on Race, sex and ethnicity on patients who have known large polyp (>1 polyps) Presentation experience in IDSA, ACP –regional meeting and MMCGME Quality forum.


Teaching Areas

  • Rheumatology
  • Hematology 


Clinical Interests

Rheumatology; Hematology