Otto Sánchez, MD

Assistant Professor of Medicine, Division of Renal Diseases and Hypertension

Otto Sánchez

Contact Info

Administrative Assistant Name
Karen Grabau

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Assistant Professor of Medicine, Division of Renal Diseases and Hypertension

Medical School, Universidad de Oriente, Cumaná, Venezuela

Fellowship, Vanderbilt University, Nashville, TN

PhD, University of Minnesota, Minneapolis, MN


Dr. Sánchez is originally from Venezuela with strong roots in Minnesota. He lived here in the mid 70’s when his father came to the U of MN to pursue a Ph.D. in genetics. He returned to Minnesota in 1997 to complete his Ph.D. in exercise physiology. He defines himself as a clinical physiologist with knowledge of epidemiology, biostatistics and magnetic resonance imaging. Dr. Sánchez uses data sets from longitudinal epidemiological studies such as the Multi Ethnic Study of Atherosclerosis (MESA) and the Coronary Artery Risk Development in Young Adults study (CARDIA) to assess risk factors for the development of renal and cardiovascular diseases. He applies his combination of skills to perform clinical research studies aimed at assessing the ability of natriuretic peptides to predict salt sensitive hypertension and the beneficial effects of natriuretic peptides on mitochondrial and microvascular function and the correlation with cardiovascular endurance and glucose metabolism in patients with peripheral arterial disease.


Research Summary/Interests

  • Diabetes
  • Natriuretic peptides
  • Hypertension
  • Peripheral arterial disease
  • The effects of exercise on health

Research Projects

  • Clinical trial entitled “Use of novel engineered natriuretic peptide (cenderitide) for the treatment of peripheral arterial disease” funded by the American Heart Association.
  • Use of NT-proBNP as a biomarker to treat salt sensitive hypertensive individuals.