Ohad Gafni

Assistant Professor, Cardiovascular Division

Ohad Gafni

Contact Info

ogafni@umn.edu

Office Phone 612-625-0967

Fax 612-301-8298

Office Address:
2231 6th Street SE
4-143 CCRB
Minneapolis, MN 55455

Administrative Assistant Name
Shawn Jarvis

Administrative Phone
612-625-9538

Administrative Email
jarvi178@umn.edu

Administrative Fax Number
612-301-8298

Assistant Professor, Cardiovascular Division


Ph.D., Weizmann Institute of Science

M.Sc., Ben-Gurion University

Summary

My academic career commenced in Ben-Gurion University of the Negev where I completed my B.Sc and M.Sc degrees in Prof. Amir Sagi laboratory. The research subject during my masters degree was the role of gastrolith Calcium binding proteins and protein-protein interactions in fresh water crayfish. During my Phd at the Weizmann Institute os Science in Dr. Jacob Hanna Laboratory, I focused on embryonic and induced pluripotent stem cells in different species by delineating the epigenetic landscape and their ability to contribute and differentiate in inter-species chimeras.

Languages

  • English
  • Hebrew

Research

Research Summary/Interests

Differentiation of human induced pluripotnet stem cells to cardivascular lineage.

Publications

  1. Weiner A., Lara-Astiaso D., Krupalnik V., Gafni O., David E., Winter D.R., Hanna J.H., Amit I. Co-ChIP enables genome-wide mapping of histone mark co-occurrence at single-molecule resolution. Nature Biotechnology, 2016. 34: 953-961.
  2. Dhar S., Lee S.H., Chen K., Zhu G., Oh W., Allton K., Gafni O., Kim Y.Z., Barton M., Hanna J.H., Wang Z., Li W., Lee M.G. An essential role for UTX in resolution and activation of bivalent promoters. Nucleic Acid Research, 2016. 44 (8): 3659-3674.
  3. Gafni O., Weinberger L., Mansour A.A, Manor Y.S., Chomsky E., Ben-Yosef D., Kalma Y., Viukov S., Maza I., Zviran A., Rais Y., Shipony Z., Mukamel Z., Krupalnik V., Zerbib M., Geula S., Caspi I., Schneir D., Shwartz T., Gilad S., Zalcenstein D.A., Benjamin S., Amit I., Tanay A., Massarwa R., Novershtern N. & Hanna J.H. Derivation of novel human ground state naive pluripotent stem cells. Nature, 2013. 504: 282-286.
  4. Rais Y., Zviran A., Geula S., Gafni O., Chomsky E., Viukov S., Mansour A.A., Caspi I., Krupalnik V., Zerbib M., Maza I., Mor N., Baran D., Weinberger L., Jaitin D.A., Astiaso D.L., Gonen R.B.., Shipony Z., Mukamel Z., Hagai T., Gilad S., Zalcenstein D.A., Tanay A., Amit I., Novershtern N. & Hanna J.H. Deterministic direct reprogramming of somatic cells to pluripotency. Nature, 2013. 502: 65-70.
  5. Mansour A.A*, Gafni O*., Weinberger L., Zviran A., Ayyash M., Rais Y., Krupalnik V., Zerbib M., Amann-Zalcenstien D., Maza I., Geula S., Viukov S., Holtzman L., Pribluda A., Canaani E., Horn-Saban S., Amit I., Novershtern N. and Hanna J.H. The H3K27 demethylase Utx regulates somatic and germ cell epigenetic reprogramming. Nature, 2012. 488: 409-413. *Equal contribution.
  6. Aziz-Boaron A., Klausner Z., Hasoksuz M., Shenkar J., Gafni O., Gelman B., David D. and Klement E. Circulation of bovine ephemeral fever in the Middle East—Strong evidence for transmission by winds and animal transport. Veterinary Microbiology, 2012. 158(3-4): 300-307.
  7. Rosen O., Manor R., Weil S., Gafni O., Linial A., Aflalo E.D. and Sagi A. A sexual shift induced by a single insulin-like gene silencing in intersex crayfish: ovarian upregulation and testicular apoptosis. Plos One, 2010. 5(12): e15281