Lin Yee Chen, MD, MS

Associate Professor of Medicine, Cardiovascular Division

Lin Yee Chen

Contact Info

Office Address:
Cardiovascular Division
Variety Club Research Center
401 East River Parkway
2nd Floor
Minneapolis, Minnesota 55455

Mailing Address:
UMN – Cardiovascular Division
420 Delaware Street SE
MMC 508 Mayo
8508A (Campus Delivery Code)
Minneapolis, MN 55455

Administrative Assistant Name

Administrative Phone

Administrative Email

Administrative Fax Number

Associate Professor of Medicine, Cardiovascular Division

Co-Director, Atrial Fibrillation Center, University of Minnesota Health Heart Care

Medical Director, Cardiac Electrophysiology Laboratory, University of Minnesota Medical Center

Chair, 2018 AHA Scientific Statement Writing Group: Atrial Fibrillation Burden—Moving Beyond Atrial Fibrillation as a Binary Entity

Cardiac Electrophysiologist, Cardiologist

Medical School, National University of Singapore, Singapore

Internal Medicine Residency, Mayo Clinic, Rochester, MN

Cardiology and Cardiac Electrophysiology Fellowship, Mayo Clinic, Rochester, MN

Master of Science in Clinical Research, University of Minnesota, Minneapolis, MN


I am a tenured Associate Professor of Medicine, an ABIM board-certified cardiac electrophysiologist, and an NIH-funded clinical investigator. My research on atrial fibrillation (AF) is focused on 2 themes: (1) To discover novel strategies to prevent AF, reduce AF burden, and prevent AF-related outcomes, and (2) To characterize the relationship of AF to outcomes such as stroke, dementia, and sudden cardiac death, and to elucidate the underlying mechanisms. As an Atherosclerosis Risk in Communities (ARIC) and Multi-Ethnic Study of Atherosclerosis (MESA) investigator, I have published and co-authored numerous papers on AF using ARIC and MESA data. Currently, I am the PI of a large multi-center project (R01HL126637) that uses the Zio XT Patch—an ambulatory heart rhythm monitor—to define the prevalence of subclinical AF in the elderly and elucidate the prognostic significance of subclinical AF and AF burden. Clinically, I provide comprehensive, evidence-based, and state-of-the-art care to patients with AF which includes performing catheter ablation to maintain sinus rhythm and left atrial appendage occlusion to prevent cardioembolic stroke.

Awards & Recognition

  • American Heart Association, 10SDG3420031, 2010-2015, Gene-Gene and Gene-Environment Interactions in Atrial Fibrillation
  • National Institute on Aging, R21AG042660, 2013-2016, Arterial Structure and Function and Atrial Fibrillation
  • National Heart, Lung, and Blood Institute, R01HL126637, 2016-2021, Significance of Atrial Fibrillation and Atrial Fibrillation Burden Detected by Novel ECG Monitoring in Community-Dwelling Elderly
  • AHC Faculty Research Development Award, 2017-2019, Moderate-Intensity Continuous Training and Sprint Interval Training in Reducing Atrial Fibrillation Burden

Professional Associations

  • Member - Management Committee, Cardiovascular Service Line, University of Minnesota Health Heart Care
  • Member - ECG & Arrhythmias Committee, Clinical Cardiology Council, American Heart Association
  • Member - Research Committee, Heart Rhythm Society
  • Member - Evidence Review Committee for the AHA/ACC 2016 Guideline for the Treatment of Syncope
  • Member - 2017 ACC/AHA/Heart Rhythm Society Guideline Focused Update on the Management of Patients With Atrial Fibrillation Writing Committee
  • Member - 2018 EHRA/HRS/APHRS/SOLAECE Expert Consensus on Arrhythmias and Cognitive Function: What is the best practice?


Research Summary/Interests

Care Philosophy
I believe in providing comprehensive and evidence-based cardiac electrophysiology care to my patients.

Research Funding Grants

Lin Yee Chen, MD, MS of the Cardiovascular Division, Department of Medicine has been awarded an R01 grant, "Significance of Atrial Fibrillation and Atrial Fibrillation Burden Detected by Novel ECG Monitoring in Community-Dwelling Elderly" from the National Heart, Lung, and Blood Institute. This is a $3.74 million grant over 5 years (2016–2021).

Dr. Chen’s study is a multi-center project that involves 2-week ambulatory heart rhythm monitoring in 4,000 participants to: (1) define the role of screening for subclinical atrial fibrillation in the elderly, (2) elucidate the relationship of atherosclerotic risk factors in mild-life to atrial fibrillation burden in older age, and (3) define the prognostic significance of atrial fibrillation burden. This project is an ancillary study to the Atherosclerosis Risk in Communities (ARIC) Study.



University of Minnesota Medical Center;University of Minnesota Physicians Heart at Fairvie

Board Certifications

  • Internal Medicine
  • Cardiology
  • Cardiac Electrophysiology

Clinical Interests

Atrial fibrillation ablation (pulmonary vein isolation); Biventricular ICD implantation; ICD implantation; PVC ablation; Supraventricular tachycardia ablation; Ventricular tachycardia ablation

Hospital Privileges

Fairview Lakes Medical Center; University of Minnesota Health Maple Grove Clinics; Fairview Ridges Hospital; Fairview Southdale Hospital; University of Minnesota Medical Center