Daniel Duprez, MD, PhD, FAHA, FACC, FESC, FASH

Professor of Medicine, Cardiovascular Division

Daniel Duprez

Contact Info

Office Address:
Cardiovascular Division
Variety Club Research Center
401 East River Parkway
2nd Floor
Minneapolis, Minnesota 55455

Mailing Address:
UMN – Cardiovascular Division
420 Delaware Street SE
MMC 508 Mayo
8508A (Campus Delivery Code)
Minneapolis, MN 55455

Administrative Assistant Name
Cheryl

Administrative Phone
612-625-7613

Administrative Email
tinch002@umn.edu

Administrative Fax Number
612-626-4411

Professor of Medicine, Cardiovascular Division


Cardiologist
Donald and Patricia Garofalo Chair in Preventive Cardiology


Medical School, University Ghent, Belgium

Residency, University Hospital Ghent, Belgium

Fellowship, University Hospital Ghent, Belgium

Fellowship, Mayo Clinic, Minneapolis, MN

Summary

"My philosophy is to provide outstanding comprehensive care to patients with cardiovascular disease, including a number of emerging technologies available at the University of Minnesota Medical Center-Fairview. My practice combines state-of-the-art therapies, compassion, and effective communication, creating a working partnership that results (overall) in high quality of life for my patients."

Awards & Recognition

  • AHA Hero Award (research), 2014
  • Minnesota Monthly "Best Doctor" (2014)
  • Best Doctors in America®, (2011-2012)
  • Jan-Frans Heymans Prize, period 1986-1987 of the Royal Academy of Medicine of Belgium
  • Prize Foundation Prof. Dr. G. Verdonck 1997-1999 of the Royal Academy of Medicine of Belgium
  • Prize of the Foundation Dr Karel-Lodewijk Verleysen, period 1998-2001 of the Royal Academy of Medicine of Belgium

Professional Associations

  • President of the National Lipid Association Midwest Chapter and Member of the Board of Directors of NLA
  • Fellow of the American Heart Association
  • Fellow of the American College of Cardiology
  • Fellow of the European Society of Cardiology
  • Fellow of the American Society of Hypertension
  • Fellow of the National Lipid Association
  • Past-USA governor of the International Society of Cardiovascular Pharmacotherapy
  • Member of scientific grant review committee for NIH (USA), FWO (Belgium), France, Italy, Canada, UK, South Africa, United Emirates, Singapore

Research

Research Summary/Interests

  • Early markers of vascular structure and function, Biomarkers, Lipids, HIB and cardiovascular disease
  • Cardiovascular clinical trials

Publications

  • Duprez DA, Neuhaus J, Tracy R, Kuller LH, Deeks SG, Orkin C, Stoehr A, Wooley IJ, Neaton JD for the INSIGHT SMART Group. N-Terminal-proB-type Natriuretic Peptide (NT-proBNP) predicts cardiovascular disease events in HIV-infected patients: results of the SMART study. AIDS 2011;25:651-657.
  • Duprez DA, Jacobs Jr DR, Lutsey PL, Bluemke DA, Brumback LC, Polak JF, Carmen A. Peralta CA, Greenland P, Kronmal RA. Association of Small Artery Elasticity with Incident Cardiovascular Disease in Older Adults: The Multi-Ethnic Study of Atherosclerosis. Am J Epidemiol. 2011;174:528-536.
  • Duprez DA, Florea, Zhong W, Grandits GA, Hawthorne CK, Hoke L, Cohn JN. Vascular and Cardiac Functional and Structural Screening to Identify Risk of Future Morbid Events: Preliminary Observations. J Am Soc Hypertens. 2011;5:401-409.
  • Duprez DA. Arterial Stiffness/Elasticity in the Contribution to Progression of Heart Failure. Heart Fail Clin. 2012;8:135-141.
  • Duprez D, Jacobs Jr DR. Arterial stiffness and left ventricular diastolic function, does sex matter? Hypertension 2012;60:283-284.
  • Chirinos JA, Kips J, Brumback L, Kronmal R, Bluemke DA, Jacobs Jr D, Duprez DA, Vermeersch S, Townsend RR, Segers P. Arterial Wave Reflections and Incident Cardiovascular Events and Heart Failure: The Multiethnic Study of Atherosclerosis. J Am Coll Cardiol 2012;60:2170-2177.
  • Duprez DA, Neuhaus J, Kuller LH, Tracy R, Belloso W, De Wit S, Drummond F, Clifford Lane H, Ledergerber B, Lundgren J, Nixon D, Paton NI, Prineas RJ, Neaton JD for the INSIGHT SMART Study G. Inflammation, Coagulation and Cardiovascular Disease in HIV-Infected Individuals. PLOS ONE 2012;7:9,e44454.
  • Saul SM, Duprez DA, Zhong W, Grandits GA, Cohn JN. Effect of carvedilol, lisinopril and their combination on vascular and cardiac health in patients with borderline blood pressure: The DETECT Study. J Hum Hypertension 2013;27:362-367.
  • Duprez DA, Hearst MO, Lutsey PL, Herrington DM, Ouyang P, Barr RG, Bluemke DA, McAllister D, Carr J, Jacobs Jr DR. Associations among Lung Function and Circulating Endothelial and Inflammation Markers: the Multi-Ethnic Study of Atherosclerosis. Hypertension 2013;61:542-548.
  • Coumbe AG, Pritzker MR, Duprez DA. Cardiovascular Risk and Psoriasis: Beyond the Traditional Risk Factors. Am J Med. 2014;127:12-18.
  • Sanchez OA, Duprez DA, Daniels LB, Maisel A, Otvos J, Folsom AR, Peralta CA, Lima JA, Bahrami B, Jacobs Jr DR.The associations between metabolic variables with NT-proBNP is blunted at pathological ranges: the multi-ethnic study of atherosclerosis. Metabolism 2014;63:475-483.
  • Miedema MD, Duprez DA, Misialek JR, Blaha MJ, Nasir K, Silverman MG, Blankstein R, Budoff MJ, Greenland P, Folsom AR. Use of Coronary Artery Calcium Testing to Guide Aspirin Utilization for Primary Prevention: Estimates From the Multi-Ethnic Study of Atherosclerosis. Circ Cardiovasc Qual Outcomes. 2014;7:453-460.
  • Zamani P, Jacobs Jr. DR, Segers P, Duprez DA, Brumback L, Kronmal R, Lilly SM, Townsend RR, Budoff M, Lima JA, Hannan P, Chirinos JA. Reflection Magnitude as a Predictor of Mortality: The Multi-Ethnic Study of Atherosclerosis. Hypertension 2014;64:958-964.
  • Kwon Y, Duprez DA, Jacobs DR, , Nagayoshi M, McClelland RL, Shahar E, Budoff M, Redline S, Shea S, Carr JJ, Lutsey PL. Obstructive Sleep Apnea and Progression of Coronary Artery Calcium: The Multi-Ethnic Study of Atherosclerosis Study. J Am Heart Assoc. 2014;3(5). pii: e001241.
  • Redheuil A, Wu CO, Yan RT, Bertoni AG, Hundley GW, Duprez DA, Jacobs Jr DR, Daniels LB, Sibley C, Bluemke DA, Lima JAC.Proximal Aortic Distensibility is an Independent Predictor of All-Cause Mortality and Incident Cardiovascular Events: The MESA Study. J Am Coll Card 2014;64:2619-2629.
  • Lehrer-Graiwer J, Singh P, Abdelbaky A, Vucic E, Korsgren M, Baruch A, Frederickson J, van Bruggen N, Tang MT, Frendeus B, Rudd JHF, Hsieh F, Ballantyne CM, Ghoshhajra B, Rosenson RS, Koren M, Roth EM, Duprez DA, Fayad ZA, Tawakol AA. FDG-PET Imaging for Oxidized LDL in Stable Atherosclerotic Disease: A Phase II Study of the Safety, Tolerability, and Anti-Inflammatory Activity. JACC Cardiovascular Imaging 2015;8:493-494.
  • Sanchez OA, Jacobs DR Jr, Bahrami H, Peralta CA, Daniels LB, Lima JA, Maisel A, Duprez DA. Increasing aminoterminal-pro-B-type natriuretic peptide precedes the development of arterial hypertension: the multi- ethnic study of atherosclerosis. J Hypertens. 2015;33:966-974.
  • Zamani P, Bluemke DA, David R. Jacobs Jr DR, Duprez DA, Kronmal R, Lilly SM, Ferrari VA, Townsend RR, Lima JA, Budoff M, Segers P, Hannan, Chirinos JA. Resistive and Pulsatile Arterial Load as Predictors of Left Ventricular Mass and Geometry: The Multi-Ethnic Study of Atherosclerosis. Hypertension 2015;65:85-92.
  • Mitchell A, Misialek J, Folsom A, Duprez D, Alonso A, Jerosch-Herold M, Watson K, Sallam T, Konety S. Usefulness of N-terminal Pro-brain Natriuretic Peptide and
  • Chirinos JA, Segers P, Duprez DA, Brumback L, Bluemke DA, Zamani P, Kronmal R, Vaidya D, Ouyang P, Townsend RR, Jacobs DR. Late systolic central hypertension as a predictor of incident heart failure: the multi- ethnic study of atherosclerosis. J Am Heart Assoc. 2015 Mar 3;4(3). pii: e001335. doi: 10.1161/JAHA.114.001335.
  • Sanchez OA, Duprez DA, Bahrami H, Peralta CA, Daniels LB, Lima JA, Maisel A, Folsom AR, Jacobs DR. Changes in N-terminal pro-B-type natriuretic peptide and incidence of diabetes: The Multi-Ethnic Study of Atherosclerosis (MESA). Diabetes Metab. 2015;41:378-386.
  • Kwon Y, Duprez DA, Jacobs DR, Nagayoshi M, McClelland RL, Shahar E, Budoff M, Redline S, Shea S, Carr JJ, Lutsey PL. Obstructive sleep apnea and progression of coronary artery calcium: the multi-ethnic study of atherosclerosis study. J Am Heart Assoc. 2014 Sep 26;3(5):e001241. doi: 10.1161/JAHA.114.001241.
  • Duprez DA, Otvos J, Tracy R, Feingold K, Greenland P, Gross MD, Lima JAC, Mackey RH, Neaton J, Sanchez OA, Jacobs DR Jr. High-Density Lipoprotein Subclasses and Noncardiovascular, Noncancer Chronic Inflammatory-Related Events Versus Cardiovascular Events: The Multi-Ethnic Study of Atherosclerosis. J Am Heart Assoc. 2015 Sep 14;4(9). pii: e002295. doi: 10.1161/JAHA.115.002295.
  • Epstein M, Duprez DA. Resistant Hypertension and the Pivotal Role for Mineralocorticoid Receptor Antagonists: A Clinical Update -2016. Am J Med. 2016;129:661-666.
  • Duprez DA, Otvos J, Sanchez OA, Mackey RH, Tracy R, Jacobs DR Jr. Comparison of the Predictive Value of GlycA and Other Biomarkers of Inflammation for Total Death, Incident Cardiovascular Events, Noncardiovascular and Noncancer Inflammatory-Related Events, and Total Cancer Events. Clin Chem. 2016;62:1020-1031.
  • Further publications

Clinical

Clinics

University of Minnesota Medical Center;University of Minnesota Physicians Heart at Fairvie

Board Certifications

Cardiology

Clinical Interests

Cardiovascular disease prevention (primary, secondary); Arterial hypertension; Lipid disorders; Early Cardiovascular Disease; Vascular diseases (arterial, venous, lymph)