Jason Bartos, MD, PhD

Assistant Professor of Medicine, Cardiovascular Division

Jason Bartos

Contact Info

Office Address:
Cardiovascular Division
Variety Club Research Center
401 East River Parkway
2nd Floor
Minneapolis, Minnesota 55455

Mailing Address:
UMN – Cardiovascular Division
420 Delaware Street SE
MMC 508 Mayo
8508A (Campus Delivery Code)
Minneapolis, MN 55455

Administrative Assistant Name
Esther Almeida

Administrative Phone

Administrative Email

Administrative Fax Number

Assistant Professor of Medicine, Cardiovascular Division


Medical School, Stanford University School of Medicine, Stanford, CA

Internal Medicine Residency, Stanford University, Stanford, CA

Cardiovascular Medicine, University of Minnesota, Minneapolis, MN

Critical Care Cardiology, University of Minnesota, Minneapolis, MN

Interventional Cardiology, University of Minnesota, Minneapolis, MN

Pharmacology, University of Iowa, Iowa City, IA

BA, St. John's University, Collegeville, MN


Dr. Jason Bartos was born and raised in Maple Plain, MN. He completed his undergraduate work in Chemistry and Psychology at St. John’s University and went on to earn his PhD in Pharmacology from the University of Iowa. He then moved to Stanford University School of Medicine where he earned his MD and completed Internal Medicine residency. He moved to the University of Minnesota in 2012 where he completed fellowships in Cardiovascular Medicine, Critical Care Cardiology, and Interventional Cardiology.  

Dr. Bartos is board-certified in internal medicine, cardiology, critical care medicine, and interventional cardiology. His clinical interests include cardiac critical care, resuscitation, advanced hemodynamic support, pulmonary embolus, and coronary artery disease and intervention.

Dr. Bartos’s research interests include resuscitation, advanced hemodynamic support, and recovery from cardiac arrest. He has performed research in the field of ischemia and reperfusion injury for 15 years describing the molecular pathways of injury in models of cerebral ischemia and investigating potential therapies to mitigate the effects of reperfusion injury in heart transplantation and myocardial infarction.

Most recently, Dr. Bartos has worked in the laboratory of Dr. Demetris Yannopoulos using clinically relevant porcine models of myocardial infarction and cardiac arrest to develop therapies which alleviate the injury incurred during ischemia and reperfusion. This work has resulted in multiple publications demonstrating improved survival and function after prolonged arrest with multiple clinically applicable therapies. In addition, Dr. Bartos has worked with Dr. Yannopoulos to develop protocols utilizing rapid transport from the field, peripherally placed veno-arterial ECMO, coronary reperfusion, and subsequent cardiac intensive care to improve outcomes for patients with refractory VT/VF cardiac arrest. This combination of clinical practice and laboratory research provides a unique opportunity to develop and pursue innovations that change clinical practice and improve patient care.

Awards & Recognition

  • American Heart Association/Resuscitation Science Symposium: Young Investigator Award. November 2015
  • Lillehei Scholar; Cardiovascular Division, University of Minnesota. July 2012-June 2015
  • Arnold P. Gold Foundation’s Humanism and Excellence in Teaching Award; Stanford Medical School. June 2011
  • American Medical Association Physicians of Tomorrow Scholarship. July 2009.


Research Summary/Interests

  • Resuscitation
  • CPR
  • Reperfusion injury
  • Cardiac Arrest
  • Advanced Hemodynamic Support (ECMO)


  • Yannopoulos, D., Bartos, J.A., Raveendran, G., Conterato, M., Frascone, R.J., Trembley, A., John, R., Connett, J., Benditt, D.G., Lurie, K.G., Wilson, R.F., Aufderheide, T.P. Burden of coronary artery disease in patients with out-of-hospital refractory ventricular fibrillation cardiac arrest. JACC. In Press.
  • Bartos, J.A., Voicu, S., Matsuura, T.R., Tsangaris, A., Sideris, G., Oestreich, B.A., George, S.A., Olson, M., Chandra Shekar, K., Rees, J.N., Carlson, K., Sebastian, P., McKnite, S., Raveendran, G., Aufderheide, T.P., Yannopoulos, D. Role of epinephrine and extracorporeal membrane oxygenation in the management of ischemic refractory ventricular fibrillation – a randomized trial in pigs. JACC BTS. In press.
  • Matsuura, T.R., Bartos, J.A., Tsangaris, A., Olson, M., McKnite, S.H., Rees, J.N., Kadambari, C.S., Beinengraeber, M., Neumar, R., Aufderheide, T., Riess, M.L., Yannopoulos, D. Effects of cardiac arrest and ischemic postconditioning during cardiopulmonary resuscitation on cardiac and brain mitochondrial function. Resuscitation. 116: 8-15, 2017. PMID 28408349
  • Moore, J.C., Bartos, J.A., Matsuura, T.R., Yannopoulos, D. The future is now: Neuroprotection during cardiopulmonary resuscitation. Curr Opin Crit Care. 23(3): 215-222, 2017. PMID 28346232
  • Yannopoulos, D., Bartos, J.A., George, S.A., Sideris, G., Voicu, S., Oestreich, B., Matsuura, T., Shekar, K., Rees, J., Aufderheide, T. Sodium nitroprusside enhanced cardiopulmonary resuscitation improves short term survival in a porcine model of ischemic refractory ventricular fibrillation. Resuscitation. 110: 6-11, 2017. PMID 27771299 
  • Bartos, J.A., Matsuura, T.R., Tsangaris, A., Olson, M., McKnite, S.H., Rees, J.N., Haman, K., Chandra Shekar, K., Riess, M.L., Bates, F.S., Metzger, J.M., Yannopoulos, D. Intracoronary poloxamer 188 prevents reperfusion injury in a porcine model of ST-segment elevation myocardial infarction. J Am Coll Cardiol Basic Trans Sci. 1(4): 224-234, 2016. PMID 27695713
  • Yannopoulos, D., Bartos, J.A., Martin, C., Raveendran, G., Missov, E., Conterato, M., Frascone, R.J., Trembley, A., Sipprell, K., John, R., George, S., Carlson, K., Brunsvold, M.E., Garcia, S., Aufderheide, T.P. The Minnesota Resuscitation Consortium’s Advanced Perfusion and Reperfusion Cardiac Life Support Strategy for Out-of-Hospital Refractory Ventricular Fibrillation. J Am Heart Assoc. 5(6): 1-10, 2016. PMID: 27412906 
  • Bartos, J.A., Matsuura, T.R., Sarraf, M., Youngquist, S.T., McKnite, S.H., Rees, J.N., Sloper, D.T., Bates, F.S., Segal, N., Debaty, G., Lurie, K.G., Neumar, R.W., Metzger, J.M., Riess, M.L., Yannopoulos, D. Bundled postconditioning therapies improve hemodynamics and neurologic recovery after 17 min of untreated cardiac arrest. Resuscitation. 87: 7-13, 2015. PMID: 25447036
  • Riess, M.L., Matsuura, T.R., Bartos, J.A., Bienengraeber, M., Aldakkak, M., McKnite, S.H., Rees, J.N., Aufderheide, T.P., Sarraf, M., Neumar, R.W., and Yannopoulos, D. Anesthetic postconditioning at the initiation of CPR improves myocardial and mitochondrial function in a pig model of prolonged untreated ventricular fibrillation. Resuscitation. 85(12): 1745-1751, 2014. PMID: 25281906
  • Bartos, J.A., Debaty, G., Matsuura, T., and Yannopoulos, D. Post-conditioning to improve cardiopulmonary resuscitation. Curr Opin Crit Care. 20(3): 242-249, 2014.
  • Francis, G.S., Bartos, J.A., and Adatya, S. Inotropes. JACC. 63(20): 2069-2078, 2014.
  • Bartos, J.A. and Francis, G.S. The high-risk patient with heart failure with reduced ejection fraction: treatment options and challenges. Clin Pharmacol Ther. 94(4): 509-518, 2013.
  • Bartos, J.A. and Yannopoulos, D. Novelties in pharmacological management of cardiopulmonary resuscitation. Curr Opin Crit Care. 19(5): 417-423, 2013.
  • Kothary, N., Bartos, J.A., Hwang, G.L., Duo, R., Kuo, W.T., Hofmann, L.V. Computed tomography-guided percutaneous needle biopsy of indeterminate pulmonary pathology: Efficacy of obtaining a diagnostic sample in immunocompetent and immunocompromised patients. Clin Lung Cancer. 11(4): 251-256, 2010.
  • Tang-Quan, K.R., Bartos, J., Deuse, T., Churchill, E., Schafer, H., Reichenspurner, H., Mochley-Rosen, D., Robbins, R.C., and Schrepfer, S. Non-volume-loaded heart provides a more relevant heterotopic transplantation model. Transpl Immunol. 23(1-2): 65-70, 2010. 
  • Bartos, J.A., Ulrich, J.D., Li, H., Beazely, M.A., Chen, Y.C., MacDonald, J.F., and Hell, J.W. Postsynaptic clustering and activation of Pyk2 by PSD-95. J Neurosci. 30(2): 449-463, 2010. PMID: 20071509



University of Minnesota Medical Center;University of Minnesota Physicians Heart at Fairview

Board Certifications

  • Internal Medicine
  • Cardiovascular Medicine
  • Critical Care Medicine
  • Interventional Cardiology

Clinical Interests

Cardiac Critical Care; Resuscitation; Advanced Hemodynamic Support; Pulmonary Embolus; Coronary Artery Disease and Intervention