Kurt Prins, MD, PhD

Assistant Professor of Medicine, Cardiovascular Division

Kurt Prins

Contact Info

Administrative Assistant Name
Jane Hutchins-Peterson

Administrative Email
jhutchin@umn.edu

Assistant Professor of Medicine, Cardiovascular Division


Cardiologist


MD, University of Minnesota, Minneapolis, MN

Internal Medicine Residency, University of Alabama-Birmingham, Birmingham, AL

Cardiovascular Disease Fellowship, University of Minnesota, Minneapolis, MN

PhD, Biochemistry, University of Minnesota, Minneapolis, MN

BS, University of Wisconsin, WI

Summary

Dr. Prins is dedicated to understanding right ventricular (RV) dysfunction in pulmonary hypertension. He studies the RV in clinical studies as well as his basic science laboratory. He has given talks at multiple international conferences and receives grant funding from the NIH.

Expertise

  • Pulmonary Hypertension
  • Right Ventricle, Cardiac Biology

Awards & Recognition

  • American Society of Clinical Investigation Young Physician-Scientist Award (2019)

  • Butrous Young Investigator Award in Pulmonary Arterial Hypertension (2019)

  • Mentored Clinical Scientist Research Career Development Award (2018-2023)
  • Yang Wang Cardiology Research Fellowship Award (2017)
  • Northwestern Cardiovascular Young Investigator Forum Finalist (2016)
  • Ruth L Kirschstein National Research Service Award (2015-2018)

Research

Research Summary/Interests

  • Pulmonary Hypertension
  • Right Ventricular Failure
  • CTEPH
  • Clinical Trial Participation
  • Pulmonary Balloon Angioplasty

Research Funding Grants

  • NIH K08 (2018-2023)

Publications

  • Prins, KW, Rose, L, Archer, SL, Weir, EK, Pritzker, M, Olson, M, and Thenappan, T. 2019. Clinical Determinants and Prognostic Implications of Right Ventricular Dysfunction in Pulmonary Hypertension due to Chronic Lung Disease. JAHA, 8: e01146
  • Prins, KW, Thenappan, T, Kalra, R, Weir, EK, Prtizker, M, and Archer, SL. 2019. Repurposing Medications for Pulmonary Arterial Hypertension: What’s Old is New Again. JAHA, 8:e011343
  • Rose L*, K.W. Prins*, S.L. Archer, M. Pritzker, E.K. Weir, and T. Thenappan. 2019. Survival in Pulmonary Hypertension due to Chronic Lung Disease: Influence of low diffusion capacity of the lung for carbon monoxide. JHLT. 38: 145-1554. Law, M, Prins, KW, M. Olander, and J.M. Metzger. 2018. Exacerbation of dystrophic cardiomyopathy by phospholamban deficiency-mediated chronically increased cardiac calcium cycling in vivo. AJP Heart. 315: H1544-H1552 
  • Prins, K.W., L. Rose, S.L. Archer, M. Pritzker, E.K. Weir, F. Kamirczak, J.R. Misialek, T. Thenappan. 2018. Disproportionate right ventricular dysfunction and poor survival in group 3 pulmonary hypertension. Am. J. Respir. Crit. Care Med., 197(11):1496-1499.
  • Prins, K.W., S. Duval, J. Markowitz, M. Pritzker, and T. Thennappan. 2017. Chronic Effects of PAH-Specific Therapy in World Health Organization Group III Pulmonary Hypertension: A Systematic Review and Meta-Analysis. Pulm Circ. 1: 145-155.
  • Prins, K.W., E.K. Weir, S.L. Archer, J. Markowitz, L. Rose, M. Pritzker, R. Madlon-Kay, and T. Thennappan. 2016. Pulmonary Pulse-wave Transit Time is Associated with Right Ventricular-Pulmonary Artery Coupling in Pulmonary Arterial Hypertension. Pulm Circ. 6: 576-585.
  • Prins, K.W., and T. Thenappan. 2016. WHO Group 1 Pulmonary Hypertension: Epidemiology and Pathophysiology. Cardiology Clinics. 34: 363-374.
  • Prins, K.W., M. Asp, H. Zhang, W. Wang, and J. Metzger. 2016. Microtubule-mediated Misregulation of Junctophilin-2 Underlies T-tubule Disruptions and Calcium Mishandling in Mdx Mice. JACC Basic to Trans Science. 3: 122-130.
  • Thenappan, T., K.W. Prins, M. Pritzker, J. Scandurra, K. Volmers, and E. Weir. 2016. The Critical Role of Pulmonary Arterial Compliance in Pulmonary Hypertension. Annals ATS. 2: 276-284.
  • Prins, K.W., J.O. Neill, J.O. Tyler, P.M. Eckman, and S. Duval. 2015. Effects of beta-blocker withdrawal in acute decompensated heart failure: A systematic review and meta-analysis. JACC Heart Fail. 3: 647-653.
  • Thenappan, T, K.W. Prins, R. Cogswell, and S. Shah. 2015. Pulmonary Hypertension Secondary to Heart Failure with Preserved Ejection Fraction. Can. J. Cardiol. 4:430-439 
  • Prins, K.W., L. Tian, D. Wu, T. Thenappan, J. Metzger, and S.L., Archer, 2017. Colchicine Depolymerizes Microtubules, Increases Junctophilin-2, and Improves Right Ventricular Function in Experimental Pulmonary Arterial Hypertension. JAHA. 6: 1-13.
  • Prins K.W., Archer SL, Weir EK, Rose L, Pritzker MR, and Thenappan T, 2017. Interleukin-6 is Independently Associated with Right Ventricular Dysfunction in Pulmonary Arterial Hypertension. JHLT. 37(3):376-384.

Teaching

Academic Interests and Focus

Cardiac Physiology

Clinical

Clinical Interests

Pulmonary Hypertension, Right Ventricular Dysfunction, CTEPH