Medical School

Rheumatic and Autoimmune Diseases

Department of Medicine

Daniel L. Mueller, MD

DOM - Rhuem - Bio - Dan Mueller

Academic Title


Clinical Title



  • Arthritis and Autoimmune Disorders (Rheumatology)


  • Rheumatology Clinic
  • University of Minnesota Health Maple Grove Clinics
  • University of Minnesota Medical Center, Fairview -- West Bank
  • University of Minnesota Medical Center, Fairview -- East Bank


Medical School
University of Wisconsin, Madison, WI

Ohio State University Hospital, Columbus, OH

University of Texas Southwestern Medical Center, Dallas, TX

Administrative Contact

General Information
E: Rheum
P: (612) 625-1155
F: (612) 624-0600

Clinic Appointments
P: (612) 626-6100
W: University of Minnesota Physicians

Mailing Address

Division of Rheumatic and Autoimmune Diseases
420 Delaware Street SE, MMC 108
Minneapolis, MN 55455

Bio Statement

Dr. Daniel Mueller is a Professor of Medicine, and Chief of Rheumatic and Autoimmune Diseases at the University of Minnesota Medical School. He undertook his medical studies at the University of Wisconsin-Madison School of Medicine, and later obtained his Internal Medicine training at the Ohio State University Hospital. In 1986, he received training in basic molecular immunology in the Laboratory of Immunology at the National Institute for Allergy and Infectious Disease, NIH, under Drs. Ronald Schwartz and William Paul. It is there that he initiated his research into fundamental mechanisms involved in the development and maintenance of immune self-tolerance. In 1990, Dr. Mueller entered the Rheumatology Training Program in the Rheumatic Diseases Division/Department of Internal Medicine at the University of Texas Southwestern Medical Center, under Dr. Peter Lipsky. Since the completion of his medical and research training, he has been on the University of Minnesota Medical School faculty. He is also a member of the Autoimmunity Program, within the University s Center for Immunology. The major focus of his academic program is the investigation of the biological and biochemical mechanisms that underlie the induction and maintenance of T- and B-cell tolerance within the peripheral immune system. His goal is the design of curative antigen-specific treatment strategies for autoimmune disease.

Research Interests

  • Biological and biochemical nature of immune self-tolerance
  • T-cell tolerance

Leadership Roles

Director, Rheumatic and Autoimmune Diseases Division

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  • Last modified on November 6, 2015