Medical School

Hematology, Oncology and Transplantation

Department of Medicine

Robert Kratzke, MD

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Academic Title

Associate Professor

Clinical Title

Medical Oncologist


  • Cancer
  • Lung and Esophageal Cancer
  • Medical Oncology


  • Masonic Cancer Clinic


Medical School
University of Washington School of Medicine
University of Wisconsin Hospitals and Clinics (Internal Medicine)
McArdle Laboratory for Cancer Research (Cancer Research); National Cancer Institute (Medical Oncology)

Administrative Contact

E: Tracy Groves
P: (612) 624-5944
F: (612) 625-6919

Mailing Address

Division of Hematology, Oncology and Transplantation
420 Delaware Street SE, MMC 480
Minneapolis, MN 55455

Bio Statement

Dr. Kratzke graduated from the University of Washington School of Medicine in 1983 and completed his residency training in Internal Medicine at the University of Wisconsin Hospital and Clinics in 1986. Between 1986 and 1988, he did research at the McArdle Laboratory for Cancer Research at the University of Wisconsin Madison in the laboratory of Dr. Jeff Ross. He was a Medical Oncology Fellow at the National Cancer Institute (NCI) of the National Institutes of Health from 1988 to 1991, and stayed at the NCI doing research with Dr Frederick Kaye until 1994. From 1993 through 1994, Dr. Kratzke was also an Assistant Professor of Medicine at the Uniformed Services University of the Health Sciences in Bethesda, MD. From 1994 to 2004, he was a Staff Physician at the Minneapolis VA Medical Center in the Section of Hematology/Oncology.

Leadership Roles
  • Vice Chair of the Cancer and Leukemia Group B Respiratory Committee
  • Board of Scientific Advisors of the Mesothelioma Applied Research Foundation
  • Fellow, American College of Physicians
  • Member, American Society of Clinical Oncology
  • Member, American Federation for Medical Research
  • The John Skoglund Chair in Lung Cancer Research (2004)
  • Outstanding Academic Mentor, University of Minnesota (2007)
  • Arete Society
  • Mentor of the Year, Hematology, Oncology and Transplant Division, University of Minnesota (2006-2007)
  • Patel MR, Sadiq AA, Jay-Dixon J, Jirakulaporn T, Jacobson BA, Farassati F, Bitterman PB, Kratzke RA.  Novel role of c-jun N-terminal kinase in regulating the initiation of cap-dependent translation.  Int J Oncol. 2012 Feb;40(2):577-82.

  • Fujioka N, Nguyen J, Chen C, Li Y, Pasrija T, Niehans G, Johnson KN, Gupta V, Kratzke RA, Gupta K. Morphine-induced epidermal growth factor pathway activation in non-small cell lung cancer.  Anesth Analg. 2011 Dec;113(6):1353-64.

  • Klein MA, Mayo KH, Kratzke RA. p16(INK4a) Peptide mimetics identified via virtual screening. Bioorg Med Chem Lett. 2010 Jan 1;20(1):403-5.

  • Whitson BA, Groth SS, Li Z, Kratzke RA, Maddaus MA. Survival of patients with distal esophageal and gastric cardia tumors: a population-based analysis of gastroesophageal junction carcinomas. J Thorac Cardiovasc Surg. 2010 Jan;139(1):43-8.

  • Williams BW, Chang JJ, Chi RM, Marker PH, Frethem CD, Le CT, Kratzke RA, Kirstein MN. Cap-dependent translation blockade and fixed dose-rate gemcitabine: Interaction in an in vitro bioreactor system. Cancer Lett. 2009 Oct 18;284(1):37-46.

  • Stish BJ, Oh S, Chen H, Dudek AZ, Kratzke RA, Vallera DA. Design and modification of EGF4KDEL 7Mut, a novel bispecific ligand-directed toxin, with decreased immunogenicity and potent anti-mesothelioma activity. Br J Cancer. 2009 Oct 6;101(7):1114-23.

  • Dudek AZ, Lesniewski-Kmak K, Larson T, Dragnev K, Isaksson R, Gupta V, Maddaus MA, Kratzke RA. Phase II trial of neoadjuvant therapy with carboplatin, gemcitabine plus thalidomide for stages IIB and III non-small cell lung cancer. J Thorac Oncol. 2009 Aug;4(8):969-75.

  • Jacobson BA, De A, Kratzke MG, Patel MR, Jay-Dixon J, Whitson BA, Sadiq AA, Bitterman PB, Polunovsky VA, Kratzke RA. Activated 4E-BP1 represses tumourigenesis and IGF-I-mediated activation of the eIF4F complex in mesothelioma. Br J Cancer. 2009 Aug 4;101(3):424-31.

  • Mathew J, Kratzke RA. Lung cancer and lung transplantation: a review. J Thorac Oncol. 2009 Jun;4(6):753-60. Review.

  • Dudek AZ, Lesniewski-Kmak K, Shehadeh NJ, Pandey ON, Franklin M, Kratzke RA, Greeno EW, Kumar P. Phase I study of bortezomib and cetuximab in patients with solid tumours expressing epidermal growth factor receptor. Br J Cancer. 2009 May 5;100(9):1379-84.

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  • Last modified on November 24, 2015