Medical School

Hematology, Oncology and Transplantation

Department of Medicine

Gregory Vercellotti, MD, FACP

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Academic Title

Professor of Medicine

Clinical Title

Hematologist / Oncologist


  • Blood Cancer
  • Cancer
  • Blood and Marrow Transplantation
  • Leukemia
  • Blood Disorders (Hematology -- Benign)
  • Hematology/Oncology


  • Blood and Marrow Transplant
  • Masonic Cancer Clinic


Medical School
University of Illinois, Chicago
University of Wisconsin, Madison
University of Minnesota (Hematology / Oncology)

Administrative Contact

E: Barbara Porwit
P: (612) 624-5620
F: (612) 625-6919

Mailing Address

Division of Hematology, Oncology and Transplantation
420 Delaware Street SE, MMC 480
Minneapolis, MN 55455

Bio Statement

Dr. Vercellotti received his medical degree from the University of Illinois College of Medicine. He was an intern and resident in internal medicine at the University of Wisconsin, Madison and had a fellowship in Hematology-Oncology at the University of Minnesota, Minneapolis.

Research Interests

Dr. Vercellotti’s research focuses on inflammation and endothelial cell biology, the role of inflammation in vaso-occlusion in sickle cell anemia, the role of infection in atherosclerosis and vascular disease, and oxidative stress and vascular disease. His clinical interests range from coagulation and bleeding disorders, platelet disorders, red cell disorders, porphyria, bone marrow transplant, leukemia, lymphoma, and myeloma to immunologic deficiencies.

Leadership Roles
  • Senior Associate Dean for Education, University of Minnesota (1997-2004)
  • Member, Biomedical Engineering Institute, University of Minnesota (2005-present)
  • Member, American Society of Hematology
  • Member, American Medical Association
  • Member, Minnesota Medical Society
  • Mpls.St. Paul Magazine "Top Doctor" (2008-2014)
  • Clinical Excellence Award, Outstanding Clinician, Department of Medicine, University of Minnesota (2014)
  • U.S. News & World Report 2012 Top Doctor
  • Alpha Omega Alpha
  • Fairview-University Outstanding Clinician of the Year (2009)
  • Golden Key International Honor Society
  • Minnesota Monthly "Best Doctors" (2014)
  • Clinical Excellence Award, Outstanding Clinician, Department of Medicine, University of Minnesota (2014)
  • Holtan S, Verneris MR, Schultz KR, Newell LF, Meyers G, He F, DeFor TE, Vercellotti GM, Slungaard A, MacMillan ML, Cooley SA, Blazar BR, Panoskaltsis-Mortari A, Weisdorf DJ. Circulating Angiogenic Factors Associated with Response and Survival in Patients with Acute Graft-Versus-Host Disease., BBMT 2015 Mar 7. pii: S1083-8791(15)00125-1. PMID: 25759146 [PubMed - as supplied by publisher]
  • Belcher JD, Chen C, Holtan MS, Nguyen J, Okeley NM, Benjamin DR, Senter PD, and Vercellotti GM. The fucosylation inhibitor, 2-fluorofucose, inhibits vaso-occlusion, leukocyte-endothelium interactions and NF-ĸB activation in transgenic sickle mice. PLoS One. 2015 Feb 23;10(2):e0117772. eCollection 2015. PMID: 25706118. PMCID: PMC4338063.
  • Vercellotti GM. Look out heme, Mac is back in town. Blood. 2014 Aug 28;124(9):1388-9. PMID:2517011
  • Bejanyan N, Oran B, Shanley R, Warlick E, Ustun C, Vercellotti G, Verneris M,. Wagner J, Weisdorf D, and Brunstein C. Clinical outcomes of acute myeloid leukemia patients relapsing after matched related donor and umbilical cord blood transplantation. Bone Marrow Transplant. 2014 Aug;49(8):1029-35. PMID: 24887379.
  • Ustun C, Reiter A, Scott BL, Nakamura R, Damaj G, Kreil S, Shanley R, Hogan W, Perales MA, Shore T, Baurmann H, Stuart R, Gruhn B, Doubek M, Hsu JW, Thoulouli E, Gromke T, Godley LA, Pagano L, Gillman A, Wagner EM, Shwayder T, Bornhäuser M, Papadopoulos EB, Böhm B, Vercellotti G, Van Lint MT, Schmid C, Rabitsch W, Pullarkat V, Legrand F, Yakoub-agha I, Barrett J, Hermine O, Hagglund H, Sperr WR, Popat U, Devine S, Deeg HJ, Weisdorf D, Akin C, Valent P. Allogeneic hematopoietic cell transplantaion is effective in advanced systemic mastocytosis. Journal Clinical Oncology. 2014 Oct 10;32(29):3264-74. PMID:25154823
  • Vercellotti GM, Belcher JD. Not simply misshapen red cells: multimolecular and cellular events in sickle vaso-occlusion. J Clin Invest. 2014 Apr 1;124(4):1462-5. PMID:24642460
  • Vercellotti GM, Khan F, Bechtel H, Nath KA, Nguyen J, Chen C, Bruzzone CM, Brown G, Steer CJ, Hebbel RP and Belcher JD. H-Ferritin ferroxidase induces cytoprotective pathways and inhibits microvascular stasis in transgenic sickle mice. Front. Pharmacol., 17 April 2014 | doi: 10.3389/fphar.2014.00079 PMID: 24860503 
  • Belcher JD, Chen C, Nguyen J, Milbauer L, Abdullla F, Alyash AI, Smith A, Nath KA, Hebbel RP, and Vercellotti GM. Heme triggers TLR4 signaling leading to endothelial activation and vaso-occlusion in murine sickle cell disease. Blood 2014. Jan 16;123(3):377-90. PMID:24277079
  • Sjeklocha L, Belcher J, Vercellotti G, Wong P and Steer C. β-globin Sleeping Beauty Transposon Reduces Red Blood Cell Sickling in a Patient-Derived CD34+-based in vitro Model . PLoS One. 2013 Nov 18;8(11):e80403. PMID:242603
  • Belcher JD, Nath KA and Vercellotti GM. Vasculotoxic and pro-inflammatory effects of plasma heme: Cell signaling and cytoprotective responses. ISRN Oxidative Medicine 2013;2013: Article ID 831596
  • Dalmasso AP, Goldish D, Tsai AK, Benson B,Wasiluk KR and Vercellotti GM IL-4 induces up-regulation of endothelial cell claudin-5 through activation of FOXO1: Role in protection from complement-mediated injury. J Biol Chem. 2014 Jan 10;289(2):838-47. PMID:24280217
  • Belcher JD, Young M, Chen C, Nguyen J, Burhop K, Tran P, Vercellotti GM. MP4CO, a pegylated hemoglobin saturated with carbon monoxide is a modulator of HO-1, inflammation and vaso-occlusion in transgenic sickle mice. Blood. 2013;122(15):2757-64. PMID: 23908468
  • Schaer DJ, Buelher PW, Alayash AI, Belcher JD and Vercellotti, GM. Hemolysis and Free Hemoglobin Revisited: Exploring hemoglobin and hemin scavengers as a novel class of therapeutic proteins. Blood 2013:121(8):1276-1284. PMID:23264591
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  • Last modified on December 7, 2015